iSalivaomicDB

Basic info

Organism	Drosophila melanogaster
Taxonomy	Insecta > Diptera > Drosophilidae > Drosophila > Drosophila melanogaster
Protein Description	Btk family kise at 29A, isoform F
Mass Weight	66749.666
Isoelectric Point	8.871

Annotation

Function

Required for proper ring cal development. Also required for the development of male genitalia and for adult survival.

Pfam

PF00017

SH2

Features

Feature key	Position	Length
Chain	1-603	603

Cross-Reference

NCBI Nucleotide	NM_001103650.2
NCBI Protein	NP_001097120.1
UniProt	P08630

Sequence

CDS[Download]

ATGATTCCCTGCGTGAGTTTGGCCGAAACGAGCGTCATTGGCAACATGAAGGAGCGGGTCAAGGAAATGAAGGTGTTCGGCTGCCGACTCAACTTCTGGAACCACATTGGTCACAGCCTGACCAGTTCCAAAACCAAAGAAGGCAACGGCAGTTCTCCAGCCCAGAATTCAACGCGCAGCATCAGTCCCAACAGCTCCACGACCAACAGTCAGTTTAGCTTGCAGCACAACAGCTCGGGGAGTCTCGGCGGAGGAGTGGGCGGCGGATTGGGAGGCGGAGGCAGCCTTGGCCTAGGCGGCGGAGGAGGAGGTGGCGGCAGTTGCACGCCCACATCGCTACAGCCTCAGTCCTCGCTGACAACTTTCAAGCAGTCCCCAACTCTATTGAACGGCAACGGAACTCTATTGGATGCCAATATGCCTGGCGGTATACCCACTCCCGGAACACCAAATTCCAAAGCCAAGGACAACTCCCACTTTGTCAAGCTGGTGGTGGCTCTCTATCCATTCAAGGCCATCGAAGGCGGCGATTTATCGCTGGAAAAGAATGCCGAATACGAAGTGATAGATGACTCACAAGAGCACTGGTGGAAGGTCAAAGATGCCTTGGGGAATGTCGGCTATATACCCAGCAACTATGTCAAGCCGAAGGCTCTTCTGGGCCTGGAGCGCTATGAATGGTATGTGGGCGACATGTCACGACAGAGAGCCGAATCGCTGCTGAAGCAAGGTGATAAGGAGGGCTGCTTTGTGGTCAGGAAGTCATCGACCAAGGGTCTCTACACACTATCGCTGCATACCAAAGTTCCACAGTCGCATGTGAAGCACTACCACATCAAGCAAAATGCTCGCTGCGAGTATTATTTGAGTGAGAAGCACTGCTGTGAAACAATTCCGGATCTGATTAACTACCATCGCCACAACTCTGGGGGTTTGGCTTGCCGACTCAAATCCTCGCCCTGCGATCGCCCAGTTCCACCGACGGCGGGATTGTCCCACGACAAATGGGAGATCCATCCGATGGAACTGATGCTGATGGAGGAGCTTGGATCGGGACAGTTTGGTGTTGTGCGGCGCGGCAAGTGGCGTGGGTCTATCGACACAGCGGTCAAGATGATGAAGGAAGGAACCATGTCCGAGGACGATTTCATTGAGGAGGCCAAGGTGATGACCAAGCTGCAGCATCCAAATCTTGTGCAGCTATATGGCGTCTGCTCCAAGCACCGGCCCATCTACATTGTGACCGAGTACATGAAGCACGGATCCTTGTTGAATTACTTGCGACGGCATGAGAAGACCCTGATTGGTAATATGGGTCTACTCCTTGACATGTGCATACAGGTTAGCAAGGGAATGACCTACCTGGAGCGCCATAACTACATTCACCGGGATCTGGCTGCCCGCAACTGTCTCGTGGGTTCCGAGAATGTCGTTAAAGTGGCCGACTTTGGATTGGCCCGATACGTTCTCGACGATCAGTATACCAGCTCTGGCGGAACCAAGTTCCCCATCAAGTGGGCCCCGCCCGAAGTGCTCAACTACACGCGCTTCTCCTCTAAGAGCGATGTGTGGGCATACGGTGTGCTGATGTGGGAGATCTTCACTTGCGGCAAGATGCCATACGGTCGCCTAAAGAATACCGAGGTTGTGGAGCGTGTGCAGCGCGGAATTATCCTAGAAAAACCAAAGTCGTGTGCCAAGGAGATTTATGATGTCATGAAGTTGTGCTGGTCACATGGACCCGAGGAGCGTCCCGCTTTCCGTGTGCTCATGGATCAGCTGGCTCTTGTGGCCCAAACGCTAACCGACTAA

Protein[Download]

MIPCVSLAETSVIGNMKERVKEMKVFGCRLNFWNHIGHSLTSSKTKEGNGSSPAQNSTRSISPNSSTTNSQFSLQHNSSGSLGGGVGGGLGGGGSLGLGGGGGGGGSCTPTSLQPQSSLTTFKQSPTLLNGNGTLLDANMPGGIPTPGTPNSKAKDNSHFVKLVVALYPFKAIEGGDLSLEKNAEYEVIDDSQEHWWKVKDALGNVGYIPSNYVKPKALLGLERYEWYVGDMSRQRAESLLKQGDKEGCFVVRKSSTKGLYTLSLHTKVPQSHVKHYHIKQNARCEYYLSEKHCCETIPDLINYHRHNSGGLACRLKSSPCDRPVPPTAGLSHDKWEIHPMELMLMEELGSGQFGVVRRGKWRGSIDTAVKMMKEGTMSEDDFIEEAKVMTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNYIHRDLAARNCLVGSENVVKVADFGLARYVLDDQYTSSGGTKFPIKWAPPEVLNYTRFSSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEIYDVMKLCWSHGPEERPAFRVLMDQLALVAQTLTD

3D Structure

Not available now!

Publication

1.	Tamkun JW, Kahn RA, Kissinger M, Brizuela BJ, Rulka C, Scott MP, Kenniso JA.; The arflike gene encodes an essential GTP-binding protein in Drosophila.; Proc tl Acad Sci U S A. 1991 Apr 15;88(8):3120-4.

Salivary Protein Card