Salivary Protein Card

Accession: Sp001584    Nitrophorin-2   [Rhodnius prolixus]
Basic info
Organism | Rhodnius prolixus |
Taxonomy | Insecta > Hemiptera > Reduviidae > Rhodnius > Rhodnius prolixus |
Protein Description | Nitrophorin-2 |
Mass Weight | 22291.805 |
Isoelectric Point | 5.814 |
Annotation
Function | Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also binds tightly to histamine, which is released by the host to induce wound healing (By similarity). | ||
Pfam |
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Features
Feature key | Position | Length |
Signal Peptide | 1-23 | 23 |
Chain | 24-202 | 179 |
Sequence
3D Structure
Not available now!
Publication
1. |
Sun J, Yamaguchi M, Yuda M, Miura K, Takeya H, Hirai M, Matsuoka H, Ando K, Watabe T, Suzuki K, Chinzei Y.; Purification, characterization and cD cloning of a novel anticoagulant of the intrinsic pathway, (prolixin-S) from salivary glands of the blood sucking bug, Rhodnius prolixus.; Thromb Haemost. 1996 Apr;75(4):573-7. |