Salivary Protein Card

Accession: Sp001588    Nitrophorin-4   [Rhodnius prolixus]
Basic info
Organism | Rhodnius prolixus |
Taxonomy | Insecta > Hemiptera > Reduviidae > Rhodnius > Rhodnius prolixus |
Protein Description | Nitrophorin-4 |
Mass Weight | 22406.001 |
Isoelectric Point | 6.808 |
Annotation
Function | Heme-based protein that delivers nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also binds tightly to histamine, which is released by the host to induce wound healing. NO release is pH dependent and linked to loop dymics. | ||
Pfam |
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Features
Feature key | Position | Length |
Signal Peptide | 1-21 | 21 |
Chain | 22-205 | 184 |
Sequence
3D Structure
Not available now!
Publication
1. |
Walker FA.; Nitric oxide interaction with insect nitrophorins and thoughts on the electron configuration of the {FeNO}6 complex.; J Inorg Biochem. 2005 Jan;99(1):216-36. 15598503 |