Salivary Protein Card
Accession: Sp001797 ADP-ribosylation factor-like protein 8 [Drosophila melanogaster]
Basic info
| Organism | Drosophila melanogaster |
| Taxonomy | Insecta > Diptera > Drosophilidae > Drosophila > Drosophila melanogaster |
| Protein Description | ADP-ribosylation factor-like protein 8 |
| Mass Weight | 21253.434 |
| Isoelectric Point | 6.737 |
Annotation
| Function | Required for normal functioning of the late endocytic pathway including lysosome motility and late endosome-lysosome fusion (PubMed:16537643, PubMed:29940804, PubMed:30115618). Not required for the delivery of lysosomal membrane protein-containing vesicles to late endosomes (PubMed:29940804). In larval motorneurons, mediates the anterograde axol long-range transport of presyptic lysosome-related vesicles required for presyptic biogenesis and syptic function (PubMed:30174114, PubMed:30115618). Essential role in chromosome segregation (PubMed:15331635). | ||
| Pfam |
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Features
| Feature key | Position | Length |
| Chain | 1-186 | 186 |
Sequence
3D Structure
Not available now!
Publication
| 1. |
Okai T, Araki Y, Tada M, Tateno T, Kontani K, Katada T.; Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation.; J Cell Sci. 2004 Sep 15;117(Pt 20):4705-15. 15331635 |