Salivary Protein Card


Accession: Sp001939    Nitrophorin-1   [Rhodnius prolixus]

Basic info
Organism Rhodnius prolixus
Taxonomy Insecta > Hemiptera > Reduviidae > Rhodnius > Rhodnius prolixus
Protein Description Nitrophorin-1
Mass Weight 22763.68
Isoelectric Point 6.81
Annotation
Function Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also binds tightly to histamine, which is released by the host to induce wound healing
Pfam
PF02087 Nitrophorin
Features
Feature key Position Length
Signal Peptide 1-23 23
Chain 24-207 184
Cross-Reference
UniProt Q26239
Sequence
MKSYTALLAVAILCLFAAVGVSGKCTKNALAQTGFNKDKYFNGDVWYVTDYLDLEPDDVPKRYCAALAAGTASGKLKEALYHYDPKTQDTFYDVSELQEESPGKYTANFKKVEKNGNVKVDVTSGNYYTFTVMYADDSSALIHTCLHKGNKDLGDLYAVLNRNKDTNAGDKVKGAVTAASLKFSDFISTKDNKCEYDNVSLKSLLTK

3D Structure
Not available now!
Publication
1. Montandon CE, Barros E, Vidigal PM, Mendes MT, Anh AC, de Oliveira Ramos HJ, de Oliveira CJ, de Siqueira CL.;
Development of data for the identification and characterization of proteins found in Rhodnius prolixus.;
Data Brief. 2016 Mar 19;7:844-7. 23721829